{"id":12243,"date":"2025-11-05T21:59:06","date_gmt":"2025-11-05T21:59:06","guid":{"rendered":"https:\/\/magazines.uthscsa.edu\/mission\/?p=12243"},"modified":"2026-01-07T21:57:25","modified_gmt":"2026-01-07T21:57:25","slug":"the-piano-that-still-plays","status":"publish","type":"post","link":"https:\/\/magazines.uthscsa.edu\/mission\/the-piano-that-still-plays\/","title":{"rendered":"The piano that still plays"},"content":{"rendered":"

The grand piano in Ann Biggs\u2019 living room was never just furniture. It was a centerpiece.<\/p>\n

For nearly half a century, \u201cMorning Has Broken\u201d drifted through the house \u2014 the song her husband, Glenn Biggs, loved most, and the soundtrack of a life they built together. Glenn was a San Antonio banker, civic leader and philanthropist whose vision helped shape how Texas advances brain health today.<\/p>\n

\u201cThat was his favorite song,\u201d said Ann, 92. \u201cIt was always the first thing he wanted me to play. I still wake up at night and hear it in my mind, even now.\u201d<\/p>\n

Today, the Biggs\u2019 piano \u2014 a gleaming Chickering grand \u2014 sits inside the UT Health San Antonio Center for Brain Health<\/a>, a $100 million facility opening in December, where science, patient care, music and community share the same space.<\/p>\n

Glenn died of Alzheimer\u2019s in 2015. When the time felt right, Ann donated the piano to bring comfort to others.<\/p>\n

\u201cMusic is one of the last things to go,\u201d she said. \u201cI saw it firsthand.\u201d<\/p>\n

When Glenn was diagnosed with Alzheimer\u2019s, she said, the disease advanced faster than either of them expected. Still, the signs were subtle enough that he could disguise them.<\/p>\n

\u201cHis neurologist said he was a type A personality, and they can cover it up for a long time,\u201d Ann recalled. \u201cAnd I think he did.\u201d<\/p>\n

As the conversations grew shorter and the silences longer, music endured. In his final months at a San Antonio memory-care center, Ann often sat at the community piano. What happened next surprised her.<\/p>\n

\u201cPatients there who never spoke would sing along with the old hymns,\u201d she said. \u201cThey remembered the words. It was remarkable.\u201d<\/p>\n

Scientists now understand what she witnessed. While Alzheimer\u2019s can blur names and faces, the neural pathways that process rhythm and melody often remain intact.<\/p>\n

\u201cMusic activates parts of the brain that connect emotion, memory and movement,\u201d said Sudha Seshadri, MD, founding director of the Glenn Biggs Institute for Alzheimer\u2019s and Neurodegenerative Diseases at UT Health San Antonio<\/a>. \u201cEven when language begins to fade, rhythm finds its way through. A familiar song can bring someone back, not just to a memory, but to themselves.\u201d<\/p>\n

A conversation that sparked a movement<\/span><\/h4>\n
\"\"
Ann Biggs continues to honor her late husband, Glenn \u2014 a San Antonio banker, civic leader and philanthropist whose vision helped shape how Texas advances brain health today. She donated her family’s grand piano to the new UT Health San Antonio Center for Brain Health, opening in December.<\/figcaption><\/figure>\n

Long before there was a building, there was a conversation.<\/p>\n

In 2014, after learning there were few options for comprehensive Alzheimer\u2019s care in South Texas, Glenn called William L. Henrich, MD, MACP, then president of UT Health San Antonio, and asked to meet.<\/p>\n

\u201cThere was nowhere to go,\u201d Ann recalled. \u201cHis doctor told us there was nothing more they could do. That\u2019s when Glenn said, \u2018We\u2019ve got to do better than this.\u2019\u201d<\/p>\n

A few days later, she drove him to UT San Antonio\u2019s Health Science Center campus and waited in the car while the two met. When he returned, Glenn told her, \u201cI think I touched a nerve.\u201d<\/p>\n

That conversation planted the seed for what would become the nationally leading Glenn Biggs Institute for Alzheimer\u2019s and Neurodegenerative Diseases and, a decade later, the new home for integrated research, care and teaching at the UT Health San Antonio Center for Brain Health.<\/p>\n

When Henrich died in 2024, the impact of his partnership with Glenn was already evident across South Texas \u2014 not in plaques but in programs, research and patients whose lives are changing because of them.<\/p>\n

\u201cDr. Henrich believed, as Glenn did, that if something needs to be done, you don\u2019t ask why. You find a way to make it happen,\u201d said Seshadri. \u201cThat spirit continues to guide every discovery and every patient we reach.\u201d<\/p>\n

It was a philosophy Glenn had lived long before the institute bore his name. Decades earlier, he persuaded the U.S. interior secretary to turn a rugged stretch of West Texas into Guadalupe Mountains National Park, a project that he realized in three years.<\/p>\n

\u201cHe didn\u2019t ask how,\u201d Ann said. \u201cHe just made it happen.\u201d<\/p>\n

A few weeks ago, her son, daughter-in-law, and granddaughters climbed to the park\u2019s summit, the highest point in Texas. Years earlier, when her sons made the same hike, a bald eagle, Glenn\u2019s favorite bird, had circled overhead. This time, they saw butterflies.<\/p>\n

\u201cThey felt like he was with them,\u201d she said softly. \u201cAnd I believe he was.\u201d<\/p>\n

Carrying a legacy forward<\/strong><\/span><\/h4>\n

Francisco G. Cigarroa, MD, senior executive vice president for health affairs and health system at UT Health San Antonio, said the work ahead reflects not only the promise of science, but the responsibility to the region it serves.<\/p>\n

Texas is home to more than 400,000 people living with Alzheimer\u2019s disease, a number projected to rise by 22% in the next decade. And San Antonio sits at the heart of one of the state\u2019s fastest-growing aging populations.<\/p>\n

\u201cIn South Texas, we face some of the highest rates of Alzheimer\u2019s and dementia in the nation, yet we also stand at the forefront of discovery and progress,\u201d Cigarroa said. \u201cThrough the Biggs Institute, the Center for Brain Health and the opportunity to advance research through the Dementia Prevention and Research Institute of Texas (DPRIT), our mission is clear. We strive to transform groundbreaking research into prevention, scientific understanding into compassionate care, and knowledge into hope for the patients and families we serve.\u201d<\/p>\n

DPRIT was approved by Texas voters this week through Proposition 14, a state constitutional amendment that established a $3 billion state fund to accelerate research, treatment and prevention of Alzheimer\u2019s disease and related dementias.<\/p>\n

Turning science into hope<\/span><\/h4>\n
\"\"
Rising at the corner of Floyd Curl and Charles Katz drives, the Center for Brain Health brings together specialists in Alzheimer’s, dementia, Parkinson’s disease and stroke.<\/figcaption><\/figure>\n

Under Seshadri’s leadership, the Biggs Institute has become a hub for early-diagnosis research and clinical trials. For her, the Center for Brain Health is more than a milestone. It’s a promise realized.<\/p>\n

\u201cWe want to find cures, but we also want to find opportunities for people to live their best lives, to keep bringing their unique personality, skill and knowledge,\u201d she said. \u201cThe Center for Brain Health is designed with that same philosophy: that medicine must care for the whole person. Mind. Body. Spirit.\u201d<\/p>\n

Rising at the corner of Floyd Curl and Charles Katz drives, the center brings together specialists in Alzheimer\u2019s, dementia, Parkinson\u2019s disease and stroke. The team includes neurologists, psychiatrists, art and music therapists, and researchers working side by side.<\/p>\n

With 91 rooms for exams, testing and treatment, along with 12 infusion chairs, the center\u2019s scientific heart is one of Texas\u2019s first Siemens Magnetom 7-Tesla TerraX scanners, capable of capturing the brain in extraordinary detail.<\/p>\n

\u201cThat MRI lets us see changes we couldn\u2019t detect before,\u201d Seshadri said. \u201cIt means catching the disease earlier, when we can still make a difference.\u201d<\/p>\n

The Center for Brain Health will also be one of a few sites in Texas offering new disease-modifying therapies.<\/p>\n

\u201cThree years ago, the FDA advisory panel voted to approve lecanemab, a new infusion therapy that removes amyloid from the brain, the toxic protein that damages neurons and helps slow the disease,\u201d Seshadri said. \u201cI learned of the approval on Glenn\u2019s birthday. It felt like a gift. We now have more than 120 patients receiving these infusions.\u201d<\/p>\n

The formal approval followed weeks later, on July 6, 2023.<\/p>\n

The therapy, she explained, is not a cure but a start. It\u2019s also a way to buy patients and families precious time. \u201cWe call these medicines disease-modifying, not symptomatic,\u201d she said. \u201cBefore, we could make memory a little better. Now, we can actually change what\u2019s happening in the brain.\u201d<\/p>\n

Soon, those infusions will be offered in rooms designed to feel more like living spaces than clinics.<\/p>\n

\u201cI imagine someone getting their infusion while a volunteer plays the piano in the next room,\u201d Seshadri said. \u201cThat\u2019s what makes the new center different.\u201d<\/p>\n

For Ann, that connection is deeply personal, a reflection of the life and love that music once carried through her home. Her beloved piano now sits in the center\u2019s Ann Biggs Community Room, its keys waiting for anyone moved to play.<\/p>\n

\u201cIt reminds us that if you can bring out joy in a person, you help keep their brain working longer,\u201d Seshadri said. \u201cMusic and art aren\u2019t extras. They\u2019re medicine in their own way.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

What began as a song in a San Antonio living room helped spark a new era of Alzheimer’s care and research in South Texas. 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