{"id":1986,"date":"2021-07-20T11:20:25","date_gmt":"2021-07-20T11:20:25","guid":{"rendered":"https:\/\/magazines.uthscsa.edu\/cancer-center\/?p=1986"},"modified":"2021-07-22T18:18:07","modified_gmt":"2021-07-22T18:18:07","slug":"childhood-chemo-alters-hearts-caretaker-cells","status":"publish","type":"post","link":"https:\/\/magazines.uthscsa.edu\/cancer-center\/2021\/07\/20\/childhood-chemo-alters-hearts-caretaker-cells\/","title":{"rendered":"Childhood Chemo Alters Heart\u2019s Caretaker Cells"},"content":{"rendered":"<figure id=\"attachment_2080\" aria-describedby=\"caption-attachment-2080\" style=\"width: 150px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-2080\" src=\"https:\/\/magazines.uthscsa.edu\/cancer-center\/wp-content\/uploads\/sites\/12\/2021\/07\/2020_Accolades_AuneG.jpg\" alt=\"\" width=\"150\" height=\"240\" \/><figcaption id=\"caption-attachment-2080\" class=\"wp-caption-text\">Gregory Aune, MD, PhD<\/figcaption><\/figure>\n<p>Cancer chemotherapy changes the function of cells that repair heart injury, researchers at the Greehey Children\u2019s Cancer Research Institute (GCCRI) at UT Health San Antonio discovered. Twenty percent of children treated with drugs called anthracyclines go on to suffer heart failure later in life.<\/p>\n<p>The journal PLOS ONE published the results Sept. 22, 2020, during Childhood Cancer Awareness Month. Study senior author Gregory Aune, MD, PhD, of the GCCRI, said they are working to understand why some children who are exposed to anthracycline therapy develop problems with the heart three to four decades later. The cardiac fibroblast, which acts as a sort of caretaker.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Senior author Gregory Aune, MD, PhD, released findings by his team showing that cancer chemotherapy changes the function of cells that repair heart injury. Twenty percent of children treated with anthracyclines suffer heart failure later in life. <\/p>\n","protected":false},"author":43,"featured_media":2071,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12],"magazine":[22],"issue-year":[48],"featured-story":[],"class_list":["post-1986","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","magazine-cancer-center","issue-year-48"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Childhood Chemo Alters Heart\u2019s Caretaker Cells - Mays Cancer Center Annual Report<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/magazines.uthscsa.edu\/cancer-center\/2021\/07\/20\/childhood-chemo-alters-hearts-caretaker-cells\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Childhood Chemo Alters Heart\u2019s Caretaker Cells - Mays Cancer Center Annual Report\" \/>\n<meta property=\"og:description\" content=\"Senior author Gregory Aune, MD, PhD, released findings by his team showing that cancer chemotherapy changes the function of cells that repair heart injury. 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